The synergistic insecticidal action of characteristic defensive substances produced by the plant family Asteraceae was investigated under controlled laboratory conditions. Sesquiterpene lactones isolated from Asteraceae that may form, through a Michael addition process, conjugates with glutathione were administered in a meridic diet to a herbivorous insect, Manduca sexta. By administering sesquiterpenes, variable in vivo reduced glutathione levels were observed in the insect larvae. When the Asteraceae-derived photooxidant α-terthienyl was co-administered, lipid peroxidation and larval mortality were significantly enhanced in the treated groups of insects with lowered in vivo glutathione levels.
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1 February 2000
Symposium-in-Print Synergistic Insecticidal Mode of Action between Sesquiterpene Lactones and a Phototoxin, α-Terthienyl
Gabriel Guillet,
Juraj Harmatha,
Thomas G. Waddell,
Bernard J. R. Philogène,
John T. Arnason
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Photochemistry and Photobiology
Vol. 71 • No. 2
February 2000
Vol. 71 • No. 2
February 2000
lipid peroxidation
sesquiterpene lactone
synergy
α-terthienyl