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1 February 2000 Symposium-in-Print Synergistic Insecticidal Mode of Action between Sesquiterpene Lactones and a Phototoxin, α-Terthienyl
Gabriel Guillet, Juraj Harmatha, Thomas G. Waddell, Bernard J. R. Philogène, John T. Arnason
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Abstract

The synergistic insecticidal action of characteristic defensive substances produced by the plant family Asteraceae was investigated under controlled laboratory conditions. Sesquiterpene lactones isolated from Asteraceae that may form, through a Michael addition process, conjugates with glutathione were administered in a meridic diet to a herbivorous insect, Manduca sexta. By administering sesquiterpenes, variable in vivo reduced glutathione levels were observed in the insect larvae. When the Asteraceae-derived photooxidant α-terthienyl was co-administered, lipid peroxidation and larval mortality were significantly enhanced in the treated groups of insects with lowered in vivo glutathione levels.

Gabriel Guillet, Juraj Harmatha, Thomas G. Waddell, Bernard J. R. Philogène, and John T. Arnason "Symposium-in-Print Synergistic Insecticidal Mode of Action between Sesquiterpene Lactones and a Phototoxin, α-Terthienyl," Photochemistry and Photobiology 71(2), 111-115, (1 February 2000). https://doi.org/10.1562/0031-8655(2000)071<0111:SIPSIM>2.0.CO;2
Received: 30 July 1999; Accepted: 1 October 1999; Published: 1 February 2000
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KEYWORDS
lipid peroxidation
sesquiterpene lactone
synergy
α-terthienyl
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